Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.69 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705060 | 0.87 | MAPT (0.79) | CRHBPCRHR2KMT2AMAPTL3MBTL1 | |
| SCHEMBL12858639 | 0.84 | CRHBP (0.66) | CRHBPCRHR2KMT2AMAPTLMNA | |
| SCHEMBL8731122 | 0.83 | MAPT (0.63) | CRHBPCRHR2KMT2AMAPTL3MBTL1 | |
| SCHEMBL19899864 | 0.80 | MAPT (0.69) | CRHBPCRHR2KMT2AMAPTL3MBTL1 | |
| SCHEMBL8727275 | 0.80 | CA1 (0.72) | CRHBPCRHR2MAPTL3MBTL1LMNA | |
| SCHEMBL4927732 | 0.80 | GAA (0.75) | KMT2AMAPTL3MBTL1LMNAGAA | |
| SCHEMBL4930245 | 0.80 | MAPT (0.69) | CRHBPCRHR2KMT2AMAPTL3MBTL1 | |
| SCHEMBL6538953 | 0.80 | CA1 (0.81) | CRHBPCRHR2KMT2AMAPTL3MBTL1 | |
| SCHEMBL7322968 | 0.80 | HTT (0.67) | CRHBPCRHR2KMT2AMAPTLMNA | |
| SCHEMBL29123185 | 0.80 | CA1 (0.67) | KMT2AMAPTL3MBTL1CA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240713-C | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-02-08 | — | — | CN | disclosed |
| CN-1296494-A | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-05-23 | — | — | CN | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |