Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.30 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371735 | 0.77 | MAPT (0.45) | — | |
| SCHEMBL2007641 | 0.70 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13837217 | 0.67 | MEN1 (0.37) | — | |
| SCHEMBL4036487 | 0.66 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL19716355 | 0.66 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18810410 | 0.66 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3820499 | 0.66 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1261572 | 0.66 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1502533 | 0.66 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL277181 | 0.66 | EGFR (0.47) | EGFRPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535104-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1996-09-04 | — | — | EP | disclosed |
| US-5276028-A | Psychological disorders, anticonvulsants, anxiolytic or hypnotics and cognition activators | NORDISK A/S (DK) | 1994-01-04 | — | — | US | disclosed |
| WO-1992000298-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-09 | — | — | WO | disclosed |