Sugi Predict

Sugi Predict / Compounds / SCHEMBL7326978

SCHEMBL7326978

SCHEMBL7326978

CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)[C@H]1CCCC[C@@H]1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KLK5 Q9Y337 3/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ REN P00797 5/20 0.48
▸ ACE P12821 1/20 0.47
▸ ATM Q13315 1/20 0.47
▸ RAB9A P51151 1/20 0.45
▸ CTSS P25774 2/20 0.45
▸ CTSL P07711 2/20 0.45
▸ CTSB P07858 1/20 0.45
▸ CTSK P43235 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7362805 1.00 KLK5 (0.55) KLK5L3MBTL1RENACEATM
SCHEMBL7357804 0.98 KLK5 (0.55) KLK5L3MBTL1RENACEATM
SCHEMBL7359025 0.98 KLK5 (0.55) KLK5L3MBTL1RENACEATM
SCHEMBL7360172 0.91 KLK5 (0.58) KLK5L3MBTL1RENACEATM
SCHEMBL10377216 0.91 KLK5 (0.58) KLK5L3MBTL1RENACEATM
SCHEMBL7325758 0.91 KLK5 (0.58) KLK5L3MBTL1RENACEATM
SCHEMBL7356966 0.85 KLK5 (0.59) KLK5L3MBTL1RENACEATM
SCHEMBL7365010 0.84 KLK5 (0.48) KLK5L3MBTL1REN
SCHEMBL7335818 0.83 KLK5 (0.58) KLK5RENATM
SCHEMBL7332548 0.82 KMT2A (0.53) KLK5L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0352000-A2 Retroviral protease binding peptides SMITHKLINE BEECHAM CORPORATION (US) 1990-01-24 — — EP disclosed