Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.80 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.80 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL7976338 | 1.00 | CRBN (0.80) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL7316123 | 1.00 | CRBN (0.80) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL21238836 | 1.00 | CRBN (0.80) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL21238842 | 1.00 | CRBN (0.80) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL1833732 | 0.98 | CRBN (0.76) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL21238727 | 0.97 | CRBN (0.84) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL21238913 | 0.95 | OR51E2 (0.75) | CRBNFKBP5OR51E2KDM4EGAA | |
| Piperidine SCHEMBL9851948 | 0.95 | OR51E2 (0.75) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL21238909 | 0.95 | OR51E2 (0.75) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL21238907 | 0.95 | OR51E2 (0.75) | CRBNFKBP5OR51E2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527761-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | Beecham Group p.l.c. (GB) | 1993-02-24 | — | — | EP | claimed |
| WO-1991015506-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | claimed |