Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.60 |
| ▸ | ADAM17 | P78536 | 18/20 | 0.51 |
| ▸ | MMP1 | P03956 | 15/20 | 0.51 |
| ▸ | MMP9 | P14780 | 10/20 | 0.51 |
| ▸ | MMP3 | P08254 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327463 | 0.92 | MMP13 (0.59) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7326429 | 0.91 | MMP13 (0.59) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7318761 | 0.91 | MMP13 (0.61) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7322691 | 0.90 | MMP13 (0.63) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7319812 | 0.89 | MMP13 (0.64) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7318485 | 0.88 | MMP13 (0.58) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7327796 | 0.88 | MMP13 (0.63) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7322936 | 0.88 | MMP13 (0.63) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7321311 | 0.87 | MMP13 (0.61) | MMP13ADAM17MMP1MMP9MMP3 | |
| SCHEMBL7317009 | 0.86 | MMP13 (0.60) | MMP13ADAM17MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387901-B1 | ANTIINFLAMMATORY AGENTS; ANTICANCER AGENTS | PFIZER INC | 2002-05-14 | — | — | US | disclosed |