Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964136 | 0.88 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7327459 | 0.85 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7396364 | 0.83 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7333917 | 0.83 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7329796 | 0.83 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7292161 | 0.82 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7336085 | 0.82 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7294704 | 0.81 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7290286 | 0.80 | PDE4B (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7295171 | 0.79 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250700-A | Phosphodiesterase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | claimed |
| US-5250700-A | Phosphodiesterase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |