Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7325730 | 0.99 | LTA4H (0.64) | LTA4HSLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL14577922 | 0.94 | LTA4H (0.56) | LTA4HSLC6A2SLC6A4SLC6A3MAP2K1 | |
| SCHEMBL27996160 | 0.92 | LTA4H (0.68) | LTA4HSLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL27722812 | 0.92 | LTA4H (0.68) | LTA4HSLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL27722831 | 0.92 | LTA4H (0.68) | LTA4HSLC6A2SLC6A4SLC6A3HRH1 | |
| SCHEMBL7327361 | 0.89 | SLC6A2 (0.53) | LTA4HSLC6A2SLC6A4SLC6A3MAP2K1 | |
| SCHEMBL2267290 | 0.88 | SLC6A2 (0.57) | LTA4HSLC6A2SLC6A4SLC6A3MAP2K1 | |
| SCHEMBL3444195 | 0.88 | SLC6A2 (0.57) | LTA4HSLC6A2SLC6A4SLC6A3MAP2K1 | |
| Hydrochloric Acid SCHEMBL7328352 | 0.88 | SLC6A2 (0.52) | LTA4HSLC6A2SLC6A4SLC6A3MAP2K1 | |
| Hydrochloric Acid SCHEMBL9555741 | 0.87 | SLC6A2 (0.56) | LTA4HSLC6A2SLC6A4SLC6A3MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674514-A1 | USE OF ARYLOXYALKYL SUBSTITUTED CYCLIC AMINES AS CALCIUM CHANNEL ANTAGONISTS AND NEW PHENYLOXYALKYL PIPERIDIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | claimed |
| CN-1091636-A | Medicine | SMITHKLINE BEECHAM PLC (GB) | 1994-09-07 | — | — | CN | claimed |
| WO-1994013291-A1 | USE OF ARYLOXYALKYL SUBSTITUTED CYCLIC AMINES AS CALCIUM CHANNEL ANTAGONISTS AND NEW PHENYLOXYALKYL PIPERIDIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1994-06-23 | — | — | WO | claimed |
| EP-0674514-A1 | USE OF ARYLOXYALKYL SUBSTITUTED CYCLIC AMINES AS CALCIUM CHANNEL ANTAGONISTS AND NEW PHENYLOXYALKYL PIPERIDIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| CN-1091636-A | Medicine | SMITHKLINE BEECHAM PLC (GB) | 1994-09-07 | — | — | CN | disclosed |
| WO-1994013291-A1 | USE OF ARYLOXYALKYL SUBSTITUTED CYCLIC AMINES AS CALCIUM CHANNEL ANTAGONISTS AND NEW PHENYLOXYALKYL PIPERIDIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1994-06-23 | — | — | WO | disclosed |