Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.57 |
| ▸ | ACE | P12821 | 10/20 | 0.57 |
| ▸ | CPA1 | P15085 | 2/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069196 | 0.90 | MME (0.63) | MMEACECPA1ACE2 | |
| SCHEMBL9069033 | 0.90 | MME (0.63) | MMEACECPA1ACE2 | |
| SCHEMBL7323041 | 0.86 | MME (0.52) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL7417464 | 0.84 | MME (0.71) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL7417457 | 0.84 | MME (0.71) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL6172437 | 0.84 | MME (0.68) | MMEACE | |
| SCHEMBL6172440 | 0.84 | MME (0.68) | MMEACE | |
| SCHEMBL7409095 | 0.83 | ACE (0.53) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL7407660 | 0.83 | ACE (0.53) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL7407664 | 0.83 | ACE (0.53) | MMEACECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474795-A | ANALGESICS, MERCAPTO-ALKANOYL AMINO ACIDS | E. R. SQUIBB & SONS, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4474799-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1984-10-02 | — | — | US | disclosed |
| US-4401677-A | Enkephalinase inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1983-08-30 | — | — | US | disclosed |
| US-4339600-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1982-07-13 | — | — | US | disclosed |
| US-4199512-A | Compounds for alleviating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4173704-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | disclosed |
| US-4140786-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4140797-A | MERCAPTOACYL AMINO ACIDS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4112119-A | MERCAPTOACYL AMINOACIDS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4053651-A | MERCAPTOACYL AMINO ACIDS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-11 | — | — | US | disclosed |