Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.71 |
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | FCER2 | P06734 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417457 | 1.00 | MME (0.71) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL7415424 | 0.96 | MME (0.72) | MMEACEFCER2 | |
| SCHEMBL7415427 | 0.96 | MME (0.72) | MMEACEFCER2 | |
| SCHEMBL7478069 | 0.87 | MME (0.55) | MMEACEFCER2 | |
| SCHEMBL7478076 | 0.87 | MME (0.55) | MMEACEFCER2 | |
| SCHEMBL7417942 | 0.84 | MME (0.53) | MMEACEFCER2 | |
| SCHEMBL7327684 | 0.84 | MME (0.57) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL7417946 | 0.84 | MME (0.53) | MMEACEFCER2 | |
| SCHEMBL7411807 | 0.84 | MME (0.58) | MMEACEFCER2 | |
| SCHEMBL7417916 | 0.84 | MME (0.58) | MMEACEFCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609310-B1 | N-(MERCAPTOACYL)AMINO ACIDS, METHODS OF THEIR PREPARATION AND THERAPEUTIC USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INST NAT SANTE RECH MED (FR) | 1998-07-29 | — | — | EP | claimed |
| US-5591891-A | PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-01-07 | — | — | US | claimed |
| EP-0609310-A1 | N-(MERCAPTOACYL)AMINO ACIDS, METHODS OF THEIR PREPARATION AND THERAPEUTIC USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-08-10 | — | — | EP | claimed |
| EP-0539848-A1 | N-(mercaptoacyl)amino acids, methods of their preparation and therapeutic use, and pharmaceutical compositions containing them | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-05-05 | — | — | EP | claimed |
| WO-1993008162-A1 | N-(MERCAPTOACYL)AMINO ACIDS, METHODS OF THEIR PREPARATION AND THERAPEUTIC USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-04-29 | — | — | WO | claimed |