Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 16/20 | 0.62 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328002 | 0.86 | P2RY12 (0.76) | PRKDCP2RY12PIK3CA | |
| SCHEMBL7328250 | 0.85 | PRKDC (0.68) | PRKDCP2RY12PIK3CA | |
| SCHEMBL7325265 | 0.83 | PRKDC (0.57) | PRKDCP2RY12PIK3CA | |
| SCHEMBL7326495 | 0.82 | PRKDC (0.57) | PRKDCP2RY12PIK3CA | |
| SCHEMBL3542889 | 0.78 | PRKDC (1.00) | PRKDCP2RY12PIK3CA | |
| SCHEMBL7327201 | 0.78 | PRKDC (0.67) | PRKDCP2RY12 | |
| SCHEMBL7320821 | 0.77 | PRKDC (0.67) | PRKDCP2RY12PIK3CA | |
| SCHEMBL3942585 | 0.77 | P2RY12 (0.74) | PRKDCP2RY12PIK3CA | |
| SCHEMBL910153 | 0.77 | PRKDC (0.84) | PRKDCP2RY12PIK3CA | |
| SCHEMBL7327041 | 0.76 | PRKDC (0.70) | PRKDCP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | claimed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | claimed |