Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319741 | 0.86 | NPC1 (0.51) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7278856 | 0.85 | KMT2A (0.45) | FKBP1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7290137 | 0.82 | TDP1 (0.46) | MEN1KMT2AHPGDRAB9ANPC1 | |
| SCHEMBL7291450 | 0.81 | FKBP1A (0.58) | FKBP1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL22951074 | 0.81 | DPP4 (0.64) | FKBP1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7269464 | 0.81 | FKBP1A (0.58) | FKBP1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10512350 | 0.81 | FKBP1A (0.58) | FKBP1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL22951072 | 0.81 | DPP4 (0.64) | FKBP1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7269457 | 0.81 | FKBP1A (0.58) | FKBP1AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7277978 | 0.80 | KDM4E (0.49) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292800-A2 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0249096-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1987-12-16 | — | — | EP | disclosed |