Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683530 | 0.99 | ACE (0.64) | ACELMNASMN1; SMN2 | |
| SCHEMBL7324077 | 0.94 | ACE (0.59) | ACELMNASMN1; SMN2 | |
| SCHEMBL7319770 | 0.92 | ACE (0.68) | ACELMNASMN1; SMN2 | |
| SCHEMBL7317912 | 0.92 | ACE (0.68) | ACELMNASMN1; SMN2 | |
| SCHEMBL7317388 | 0.92 | ACE (0.68) | ACELMNASMN1; SMN2 | |
| SCHEMBL7319777 | 0.92 | ACE (0.68) | ACELMNASMN1; SMN2 | |
| SCHEMBL7317915 | 0.92 | ACE (0.68) | ACELMNASMN1; SMN2 | |
| SCHEMBL7317394 | 0.92 | ACE (0.68) | ACELMNASMN1; SMN2 | |
| SCHEMBL7330553 | 0.91 | ACE (0.69) | ACELMNASMN1; SMN2 | |
| SCHEMBL7330560 | 0.91 | ACE (0.69) | ACELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279750-B1 | AMINOACID DERIVATIVES AS ANTIHYPERTENSIVES | Asahi Breweries, Ltd. (JP) | 1993-01-20 | — | — | EP | disclosed |