Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.39 |
| ▸ | HRH1 | P35367 | 8/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651685 | 1.00 | HTR2A (0.39) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL8651365 | 1.00 | HTR2A (0.39) | HTR2AHRH1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL8651612 | 0.85 | HTR2A (0.44) | HTR2AHRH1HTR2C | |
| SCHEMBL7330931 | 0.85 | HTR2A (0.44) | HTR2AHRH1HTR2C | |
| SCHEMBL8653237 | 0.83 | HTR2A (0.48) | HTR2AHRH1 | |
| SCHEMBL7329303 | 0.83 | HTR2A (0.48) | HTR2AHRH1 | |
| SCHEMBL8652379 | 0.83 | HTR2A (0.42) | HTR2AHRH1HTR2C | |
| SCHEMBL8653058 | 0.81 | HTR2A (0.40) | HTR2AHRH1HTR2C | |
| SCHEMBL7329595 | 0.81 | HTR2A (0.40) | HTR2AHRH1HTR2C | |
| SCHEMBL8656929 | 0.81 | HTR2A (0.38) | HTR2AHRH1HTR2CSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |