Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653237 | 1.00 | HTR2A (0.48) | HTR2APOLBKMT2AHRH1SMPD1 | |
| SCHEMBL7329595 | 0.90 | HTR2A (0.40) | HTR2AHRH1LTA4H | |
| SCHEMBL8653058 | 0.90 | HTR2A (0.40) | HTR2AHRH1LTA4H | |
| SCHEMBL8651612 | 0.89 | HTR2A (0.44) | HTR2AHRH1 | |
| SCHEMBL7330931 | 0.89 | HTR2A (0.44) | HTR2AHRH1 | |
| SCHEMBL8652132 | 0.87 | POLB (0.44) | HTR2APOLBKMT2AALDH1A1LTA4H | |
| SCHEMBL7335024 | 0.87 | POLB (0.44) | HTR2APOLBKMT2AALDH1A1LTA4H | |
| SCHEMBL7365725 | 0.87 | MEN1 (0.48) | KMT2A | |
| SCHEMBL7328038 | 0.87 | MEN1 (0.48) | KMT2A | |
| SCHEMBL7333179 | 0.87 | MEN1 (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |