Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.56 |
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303584 | 0.83 | KDM4E (0.55) | ACHEMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL7294371 | 0.76 | MAOB (0.56) | ACHEMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL26743702 | 0.74 | HPGD (0.78) | ACHEMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL7423689 | 0.72 | MAOB (1.00) | ACHEMAOBMAOA | |
| SCHEMBL7301269 | 0.70 | ACHE (0.78) | ACHEMAOBMAOA | |
| SCHEMBL7292527 | 0.70 | MAOB (0.66) | ACHEMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL11099484 | 0.70 | ACHE (0.66) | ACHEMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL28463972 | 0.70 | KDM4E (0.69) | ACHEMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL15842938 | 0.70 | KDM4E (1.00) | ACHEMAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL22733326 | 0.69 | KDM4E (0.77) | ACHEMAOBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363796-B1 | HETEROCYCLICALLY SUBSTITUTED ALKOXYCOUMARINES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL AGENTS CONTAINING SAME | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5227392-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | disclosed |
| US-5073563-A | Enzyme inhibitors, CNS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |
| EP-0363796-A1 | Heterocyclically substituted alkoxycoumarines, method for their preparation and therapeutical agents containing same | BASF Aktiengesellschaft (DE) | 1990-04-18 | — | — | EP | disclosed |