Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535202 | 0.74 | — | — | |
| SCHEMBL28064835 | 0.67 | MEN1 (0.31) | KMT2A | |
| SCHEMBL3658647 | 0.65 | NPSR1 (0.33) | — | |
| SCHEMBL27395388 | 0.65 | LMNA (0.30) | — | |
| SCHEMBL24328855 | 0.61 | — | — | |
| SCHEMBL5800447 | 0.60 | MEN1 (0.32) | KMT2A | |
| SCHEMBL28738277 | 0.60 | KDM4E (0.31) | KMT2A | |
| SCHEMBL6588622 | 0.60 | NPSR1 (0.33) | — | |
| SCHEMBL13645886 | 0.58 | NPSR1 (0.32) | KMT2A | |
| SCHEMBL29130638 | 0.57 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664805-A1 | HETEROCYCLIC -ESTERS OR -AMIDES USED AS 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008994-A1 | HETEROCYCLIC -ESTERS OR -AMIDES USED AS 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-04-28 | — | — | WO | disclosed |