Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359182 | 0.86 | HDAC4 (0.42) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL10713649 | 0.86 | HDAC4 (0.42) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL7331006 | 0.86 | HDAC4 (0.42) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL9221868 | 0.84 | EPHX1 (0.48) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL1424928 | 0.84 | EPHX1 (0.48) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL9822629 | 0.83 | EPHX1 (0.44) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL3389395 | 0.82 | EPHX1 (0.46) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL16681191 | 0.80 | CTSS (0.47) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL1853356 | 0.80 | CTSS (0.47) | CTSKCTSSHDAC4HDAC1HDAC6 | |
| SCHEMBL6690998 | 0.80 | CTSS (0.47) | CTSKCTSSHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049164-A | Suppress Aminooligohydroxy derivatives of feritin and preparation method thereof | HOECHST AG (DE) | 1991-02-13 | — | — | CN | disclosed |
| EP-0410278-A1 | Renin inhibiting aminooligohydroxy-derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-30 | — | — | EP | disclosed |