Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7331373 | 0.99 | GRIN2B (0.67) | GRIN2BSIGMAR1DRD2DRD3POLB | |
| SCHEMBL7325905 | 0.92 | GRIN2B (0.70) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| Hydrochloric Acid SCHEMBL7336883 | 0.91 | GRIN2B (0.68) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| SCHEMBL7328248 | 0.91 | GRIN2B (0.70) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| SCHEMBL7329677 | 0.90 | GRIN2B (0.69) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| Hydrochloric Acid SCHEMBL7329715 | 0.90 | GRIN2B (0.69) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| Hydrochloric Acid SCHEMBL7334760 | 0.89 | GRIN2B (0.67) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| Hydrochloric Acid SCHEMBL7326858 | 0.89 | GRIN2B (0.67) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| Hydrochloric Acid SCHEMBL7329362 | 0.89 | GRIN2B (0.67) | GRIN2BSIGMAR1DRD2DRD3GRIN1 | |
| Hydrochloric Acid SCHEMBL7333173 | 0.89 | GRIN2B (0.67) | GRIN2BSIGMAR1DRD2DRD3GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |