Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.55 |
| ▸ | DRD4 | P21917 | 6/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313373 | 0.85 | DRD2 (0.64) | DRD2DRD4DRD3L3MBTL1WDR5 | |
| SCHEMBL5929468 | 0.82 | DRD2 (0.68) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL3805304 | 0.82 | DRD2 (0.68) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL11104455 | 0.81 | CA12 (0.52) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL9011831 | 0.80 | DRD2 (0.65) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL9011652 | 0.80 | DRD2 (0.65) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL12570291 | 0.78 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1WDR5 | |
| SCHEMBL4239666 | 0.78 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1WDR5 | |
| SCHEMBL109524 | 0.78 | DRD2 (0.63) | DRD2DRD4DRD3L3MBTL1KCNH2 | |
| SCHEMBL21185868 | 0.78 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443560-A2 | HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-08-28 | — | — | EP | claimed |
| EP-0443560-A2 | HIV protease inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-08-28 | — | — | EP | disclosed |