Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323062 | 1.00 | REN (0.62) | REN | |
| SCHEMBL9833483 | 1.00 | REN (0.62) | REN | |
| SCHEMBL7312512 | 0.93 | REN (0.64) | REN | |
| SCHEMBL7312520 | 0.93 | REN (0.64) | REN | |
| SCHEMBL9442912 | 0.91 | REN (0.59) | REN | |
| SCHEMBL9442934 | 0.88 | REN (0.59) | REN | |
| SCHEMBL7361787 | 0.88 | REN (0.59) | REN | |
| SCHEMBL10448071 | 0.86 | REN (0.52) | REN | |
| SCHEMBL10448073 | 0.86 | REN (0.52) | REN | |
| SCHEMBL9556412 | 0.83 | REN (0.49) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268374-A | Containing both amide and hydroxy groups | ABBOTT LABORATORIES (US) | 1993-12-07 | — | — | US | disclosed |
| EP-0437508-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0364804-A1 | Non-peptide renin inhibitors | ABBOTT LABORATORIES (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1990003971-A1 | NON-PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-04-19 | — | — | WO | disclosed |