Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325658 | 0.91 | ALDH1A1 (0.51) | KCNH2MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7331140 | 0.91 | ALDH1A1 (0.47) | KCNH2MAPTLMNAALDH1A1CYP1A2 | |
| Fumaric Acid SCHEMBL7331293 | 0.86 | ALDH1A1 (0.45) | KCNH2MAPTALDH1A1CYP1A2CYP2D6 | |
| Fumaric Acid SCHEMBL7331303 | 0.86 | ALDH1A1 (0.45) | KCNH2MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7322721 | 0.84 | POLB (0.50) | KCNH2MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL7329615 | 0.83 | POLB (0.47) | KCNH2MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7331471 | 0.83 | ALDH1A1 (0.55) | KCNH2MAPTLMNAALDH1A1CYP1A2 | |
| SCHEMBL7329843 | 0.82 | POLB (0.60) | KCNH2MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7326199 | 0.81 | MEN1 (0.46) | KCNH2MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7330597 | 0.81 | KCNH2 (0.49) | KCNH2MAPTALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355583-A2 | Cardiotonics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |