Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651226 | 1.00 | KMT2A (0.46) | KMT2AL3MBTL1EPHX2CA12CA1 | |
| SCHEMBL7335350 | 0.89 | PPARA (0.46) | KMT2AL3MBTL1EPHX2CA12CA1 | |
| SCHEMBL7327712 | 0.89 | PPARA (0.46) | KMT2AL3MBTL1EPHX2CA12CA1 | |
| SCHEMBL7328072 | 0.89 | PPARA (0.46) | KMT2AL3MBTL1EPHX2CA12CA1 | |
| SCHEMBL8652209 | 0.89 | KMT2A (0.46) | KMT2AL3MBTL1EPHX2CA12CA1 | |
| SCHEMBL7329129 | 0.89 | KMT2A (0.46) | KMT2AL3MBTL1EPHX2CA12CA1 | |
| SCHEMBL7335848 | 0.81 | KMT2A (0.42) | KMT2AL3MBTL1EPHX2KDM1AMAOB | |
| SCHEMBL7371578 | 0.81 | HRH1 (0.42) | KMT2AL3MBTL1EPHX2KDM1AMAOB | |
| SCHEMBL8651847 | 0.81 | NPY5R (0.40) | KMT2AL3MBTL1EPHX2CA12CA1 | |
| SCHEMBL7396204 | 0.81 | NPY5R (0.40) | KMT2AL3MBTL1EPHX2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | disclosed |
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |