SCHEMBL73289

SCHEMBL73289

Nc1cc(Cl)cnc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29657163 1.00
SCHEMBL362099 0.79
SCHEMBL30297014 0.79
SCHEMBL29960628 0.79
SCHEMBL7353278 0.79
SCHEMBL14302520 0.77
SCHEMBL13983068 0.75
SCHEMBL221321 0.75
SCHEMBL305682 0.75
SCHEMBL7992204 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117510429-A Compound containing methyl isoxazole structure, and preparation method and application thereof 中国农业大学 2024-02-06 CN claimed
CN-117460727-A Process for producing dihydropyridazine-3, 5-dione derivative 中外制药株式会社 2024-01-26 CN claimed
US-20090170847-A1 Imidazopyridine Derivatives Inhibiting Protein Kinase Activity, Method for the Preparation Thereof and Pharmaceutical Composition Containing Same YUYU PHARMA, INC. (KR) 2009-07-02 US claimed
EP-1984370-A1 IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Crystalgenomics, Inc. (KR) 2008-10-29 EP claimed
WO-2007083978-A1 IMIDAZOPYRIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME CRYSTALGENOMICS, INC. (KR) 2007-07-26 WO claimed
EP-0178260-B1 PROCESS FOR THE PREPARATION OF FLUORINATED PYRIDINE DERIVATIVES CIBA-GEIGY AG (CH) 1990-05-16 EP claimed
JP-7165718-A None JP disclosed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4746964-A1 NEW PYRAZOLOPYRIDINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
US-20260116878-A1 INDAZOLE INHIBITORS OF THE WNT SIGNAL PATHWAY AND THERAPEUTIC USES THEREOF BIOSPLICE THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-4727934-A1 TREM2 AGONISTS F. Hoffmann-La Roche AG (CH) 2026-04-22 EP disclosed
WO-2026046976-A1 PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) F. HOFFMANN-LA ROCHE AG (CH) 2026-03-05 WO disclosed
US-12558428-B2 Heterobifunctional compounds and their use in treating disease HALDA THERAPEUTICS OPCO, INC. (US) 2026-02-24 US disclosed
US-4935051-A POSTEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-06-19 US disclosed
EP-0178260-B1 PROCESS FOR THE PREPARATION OF FLUORINATED PYRIDINE DERIVATIVES CIBA-GEIGY AG (CH) 1990-05-16 EP disclosed
US-4831148-A DIAZOTISING A 3-AMINO-2-HALOPYRIDINE IN PRESENCE OF HYDROGEN FLUORIDE CIBA-GEIGY CORPORATION (US) 1989-05-16 US disclosed
CN-86104887-A (R)-2-[4-(5-chloro-3-fluorine pyridine-2-base oxygen) phenoxy group] the propionic acid propargyl ester the preparation method and as herbicide applications 1987-12-23 CN disclosed
EP-0248968-A1 (R)-2-[4-(5-chloro-3-fluoropyridin-2-yloxy)-phenoxy]-propionic acid propynyl ester endowed with a herbicidal activity CIBA-GEIGY AG (CH) 1987-12-16 EP disclosed
US-4713109-A 2-(4-(5-chloro-3-fluoropyridin-2-yloxy)phenoxy)-propionic acid-propynyl ester with herbicidal activity CIBA GEIGY CORPORATION (US) 1987-12-15 US disclosed
EP-0178260-A2 Process for the preparation of fluorinated pyridine derivatives CIBA-GEIGY AG (CH) 1986-04-16 EP disclosed