⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297014 | 1.00 | — | — | |
| SCHEMBL27957344 | 0.79 | PLAU (0.47) | — | |
| SCHEMBL120637 | 0.79 | — | — | |
| SCHEMBL29657163 | 0.79 | — | — | |
| SCHEMBL30838764 | 0.79 | — | — | |
| SCHEMBL73289 | 0.79 | — | — | |
| SCHEMBL14302520 | 0.77 | — | — | |
| SCHEMBL9118637 | 0.75 | — | — | |
| SCHEMBL362876 | 0.75 | — | — | |
| SCHEMBL892755 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894349-A | Synthetic method of 2, 3-difluoro-5-chloropyridine | 济宁康盛彩虹生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| US-20130102049-A1 | REMOVABLE SACCHARIDE-BENZIMIDAZOLE (BIM) TAGS AND CONJUGATES THEREOF VIA 1H-POSITION OF THE BENZIMIDAZOLES | ACADEMIA SINICA (TW) | 2013-04-25 | — | — | US | claimed |
| US-12157727-B2 | Substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors | MERCK SHARP & DOHME LLC (US) | 2024-12-03 | — | — | US | disclosed |
| US-12030885-B2 | Substituted imidazo[2,1-f][1,2,4]triazines as PI3K-gamma inhibitors | INCYTE CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| WO-2024008196-A1 | CLASS OF AMIDE COMPOUNDS AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2024-01-11 | — | — | WO | disclosed |
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |
| WO-2023229378-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |
| EP-3661909-B1 | NOVEL SUBSTITUTED PHENYL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-3661909-B1 | NOVEL SUBSTITUTED PHENYL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-3461825-B1 | NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES | C&C RES LAB (KR) | 2023-06-07 | — | — | EP | disclosed |
| US-4582837-A | Imidazo[4,5-b] and [4,5-c]pyridine derivatives having cardiotonic activity | DR. KARL THOMAE GMBH (DE) | 1986-04-15 | — | — | US | disclosed |
| EP-0098448-A2 | Imidazole derivatives, their preparation and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1984-01-18 | — | — | EP | disclosed |
| US-4082845-A | SEROTONINMIMETICS USEFUL AS ANORECTIC, ANTIDEPRESSANT, ANALGESIC AND HYPNOTIC AGENTS | MERCK & CO., INC. (US) | 1978-04-04 | — | — | US | disclosed |
| US-4002761-A | ANTHELMINTIC AGENTS, FUNGICIDAL AGENTS | SMITHKLINE CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-4000285-A | ANTHELMINTICS | SMITHKLINE CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3985891-A | CARDIOTONICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-10-12 | — | — | US | disclosed |
| US-3962263-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3961063-A | ANTHELMINTICS | SMITHKLINE CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3935195-A | FLUORESCENT DYE | STERLING DRUG INC. (US) | 1976-01-27 | — | — | US | disclosed |