Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoxaline SCHEMBL30320908 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL5315 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL6928518 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL29355228 | 0.96 | ALDH1A1 (0.58) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL2431603 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL5358841 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL16053848 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL19877228 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL9171618 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB | |
| Quinoxaline SCHEMBL4000710 | 0.93 | ALDH1A1 (0.55) | ALDH1A1MAPTNCF1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |