Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 8/20 | 0.59 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.59 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.59 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329102 | 1.00 | ABCC9 (0.59) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7331784 | 0.88 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7331787 | 0.88 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7331778 | 0.88 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7354720 | 0.87 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7354715 | 0.87 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7354731 | 0.87 | ABCC9 (0.57) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7319016 | 0.87 | ABCC9 (0.63) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7319009 | 0.87 | ABCC9 (0.63) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7320898 | 0.86 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355565-A1 | 6-Benzoyl-substituted 3,4-dihydro-2H-benzopyranes, method for their preparation and pharmaceutical preparations based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-28 | — | — | EP | disclosed |