SCHEMBL7329265

SCHEMBL7329265

CCCCCCCc1ccc(-c2ccc(C(=O)C(=O)O)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.77
MEN1 O00255 1/20 0.77
ALDH1A1 P00352 1/20 0.77
RARA P10276 1/20 0.77
MAPT P10636 1/20 0.77
MTOR P42345 1/20 0.77
KMT2A Q03164 1/20 0.77
THRA P10827 3/20 0.65
THRB P10828 3/20 0.65
HAO1 Q9UJM8 1/20 0.61
PLA2G1B P04054 6/20 0.57
ATG4B Q9Y4P1 6/20 0.57
CYP1A2 P05177 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
RECQL P46063 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4189892 1.00 RARB (0.77) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL28494516 0.88 RARB (0.66) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL8536621 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL8533917 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL11113720 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL23484727 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL8531633 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL3088908 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL7542464 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL4174144 0.87 RARB (1.00) RARBMEN1ALDH1A1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1203089-C New compound FUJISAWA PHARMACEUTICAL CO (JP) 2005-05-25 CN disclosed
EP-0788511-B1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO (JP) 2002-12-11 EP disclosed
US-6265536-B1 MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-07-24 US disclosed
US-6107458-A FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-08-22 US disclosed
CN-1168675-A Novel compounds FUJISAWA PHARMACEUTICAL CO (JP) 1997-12-24 CN disclosed
EP-0788511-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-08-13 EP disclosed
WO-1996011210-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-04-18 WO disclosed