SCHEMBL28494516

SCHEMBL28494516

CCCCc1ccc(C(=O)C(=O)O)cc1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.66
ALDH1A1 P00352 3/20 0.61
HPGD P15428 1/20 0.61
HSD17B10 Q99714 1/20 0.61
PLK1 P53350 1/20 0.61
THRA P10827 5/20 0.60
THRB P10828 5/20 0.60
MEN1 O00255 1/20 0.57
RARA P10276 1/20 0.57
MAPT P10636 1/20 0.57
MTOR P42345 1/20 0.57
KMT2A Q03164 1/20 0.57
TRPV1 Q8NER1 1/20 0.57
HAO1 Q9UJM8 1/20 0.57
PLA2G1B P04054 2/20 0.54
ATG4B Q9Y4P1 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13950912 0.90 RARB (0.67) RARBALDH1A1HPGDHSD17B10PLK1
SCHEMBL2564366 0.90 RARB (0.67) RARBALDH1A1HPGDHSD17B10PLK1
SCHEMBL29062361 0.88 L3MBTL1 (0.59) RARBALDH1A1PLK1THRATHRB
SCHEMBL4189892 0.88 RARB (0.77) RARBALDH1A1THRATHRBMEN1
SCHEMBL7329265 0.88 RARB (0.77) RARBALDH1A1THRATHRBMEN1
SCHEMBL181230 0.84 RARB (0.89) RARBALDH1A1HPGDHSD17B10PLK1
SCHEMBL28017840 0.83 RARB (0.59) RARBALDH1A1HPGDHSD17B10PLK1
SCHEMBL9337767 0.82 RARB (0.86) RARBALDH1A1HPGDHSD17B10PLK1
SCHEMBL2849969 0.82 THRA (0.77) RARBALDH1A1THRATHRBMEN1
SCHEMBL5448932 0.82 RARB (0.86) RARBALDH1A1HPGDHSD17B10PLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN claimed
CN-111978201-A Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2020-11-24 CN claimed
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN disclosed
CN-111978201-A Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2020-11-24 CN disclosed