Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335024 | 1.00 | POLB (0.44) | POLBKDM4AUSP2ALOX15KDM4C | |
| SCHEMBL8653237 | 0.87 | HTR2A (0.48) | POLBHTR2AKMT2ALTA4HALDH1A1 | |
| SCHEMBL7365725 | 0.85 | MEN1 (0.48) | KDM4CSLC6A2KMT2AHRH3RAB9A | |
| SCHEMBL7328038 | 0.85 | MEN1 (0.48) | KDM4CSLC6A2KMT2AHRH3RAB9A | |
| SCHEMBL8653058 | 0.85 | HTR2A (0.40) | HTR2AHTR2CLTA4H | |
| SCHEMBL7329468 | 0.84 | HTR2A (0.38) | KDM4CHTR2AKMT2AMEN1 | |
| SCHEMBL8654253 | 0.84 | HTR2A (0.38) | KDM4CHTR2AKMT2AMEN1 | |
| SCHEMBL8651612 | 0.84 | HTR2A (0.44) | HTR2AHTR2C | |
| SCHEMBL7330931 | 0.84 | HTR2A (0.44) | HTR2AHTR2C | |
| SCHEMBL7331142 | 0.82 | HTR2A (0.38) | HTR2ASLC6A2HTR2CSLC6A4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-B1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-07 | — | — | EP | disclosed |