Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970263 | 0.92 | S1PR3 (0.61) | TP53HTTCYP19A1ALDH1A1MAPT | |
| SCHEMBL28745869 | 0.91 | S1PR3 (0.63) | TP53HTTCYP19A1ALDH1A1S1PR3 | |
| SCHEMBL13440156 | 0.89 | CYP19A1 (0.55) | TP53HTTCYP19A1ALDH1A1MAPT | |
| SCHEMBL18113435 | 0.88 | HTT (0.57) | TP53HTTALDH1A1MAPTCTSV | |
| SCHEMBL5133113 | 0.88 | TP53 (0.51) | TP53HTTALDH1A1MAPTS1PR3 | |
| SCHEMBL5047690 | 0.87 | ALDH1A1 (0.50) | TP53HTTALDH1A1MAPTCTSV | |
| SCHEMBL6481916 | 0.87 | CYP19A1 (0.51) | TP53HTTCYP19A1ALDH1A1MAPT | |
| SCHEMBL16957105 | 0.87 | CYP19A1 (0.53) | TP53HTTCYP19A1ALDH1A1MAPT | |
| SCHEMBL733055 | 0.86 | CYP19A1 (0.53) | CYP19A1ALDH1A1MAPTCYSLTR2CYSLTR1 | |
| SCHEMBL7562414 | 0.85 | CYP19A1 (0.52) | CYP19A1ALDH1A1MAPTCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138357-B2 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | GIULIANI INTERNATIONAL LIMITED (IE) | 2012-03-20 | — | — | US | disclosed |
| US-20090118357-A1 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | GIULIANI INTERNATIONAL LIMITED (IE) | 2009-05-07 | — | — | US | disclosed |
| EP-0442204-A2 | Pyrimidopyrimidine derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118357-A1 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field | EGFR, ERBB3, FGFR3 | TP53 1378/4885HTT 3509/4885CYP19A1 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.