Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331473 | 0.88 | PPARA (0.72) | PPARAALOX5 | |
| SCHEMBL7334028 | 0.87 | PPARA (0.71) | PPARAALOX5 | |
| SCHEMBL7321487 | 0.86 | PPARA (0.77) | PPARAMEN1LMNAMAPTKMT2A | |
| SCHEMBL7333757 | 0.85 | PPARA (0.67) | PPARAALOX5 | |
| SCHEMBL2837046 | 0.85 | PPARA (0.79) | PPARAMEN1MAPTKMT2AALOX5 | |
| SCHEMBL7331187 | 0.83 | PPARA (1.00) | PPARAMEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL7331454 | 0.81 | PPARA (0.72) | PPARAALOX5 | |
| SCHEMBL7325872 | 0.81 | PPARA (0.82) | PPARAMEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL7324266 | 0.81 | PPARA (0.82) | PPARAMEN1USP2LMNAMAPT | |
| SCHEMBL7334889 | 0.81 | PPARA (0.62) | PPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567267-A | α-Phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-01-28 | — | — | US | claimed |
| US-4567267-A | α-Phenyl-2-(aza)benzothiazolylthioglycolic acids and derivatives thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |