Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319671 | 0.90 | SLC6A2 (0.45) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| Oxalic Acid SCHEMBL7441568 | 0.89 | OPRD1 (0.44) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9768345 | 0.88 | SLC6A2 (0.46) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL7442255 | 0.88 | SLC6A2 (0.52) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL7442269 | 0.88 | SLC6A2 (0.52) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| Formic Acid SCHEMBL21381648 | 0.87 | OPRD1 (0.45) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7325604 | 0.87 | OPRD1 (0.53) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21382056 | 0.87 | OPRD1 (0.53) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30149800 | 0.87 | OPRD1 (0.53) | OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21382026 | 0.87 | OPRD1 (0.53) | OPRD1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |