Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554999 | 0.94 | REN (0.57) | REN | |
| SCHEMBL9554990 | 0.94 | REN (0.57) | REN | |
| SCHEMBL7332688 | 0.93 | REN (0.57) | REN | |
| SCHEMBL7327140 | 0.93 | REN (0.58) | REN | |
| SCHEMBL6013387 | 0.90 | REN (0.57) | REN | |
| SCHEMBL7331453 | 0.90 | REN (0.51) | REN | |
| SCHEMBL10421591 | 0.90 | REN (0.56) | REN | |
| SCHEMBL10421552 | 0.89 | REN (0.56) | REN | |
| SCHEMBL7290908 | 0.89 | REN (0.52) | REN | |
| SCHEMBL7326484 | 0.89 | REN (0.52) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | claimed |
| JP-3204860-A | — | — | None | — | — | JP | disclosed |
| JP-H03204860-A | NEW AMINO ACID DERIVATIVE HAVING RENIN-INHIBITING ACTIVITY | JAPAN TOBACCO INC | 1991-09-06 | — | — | JP | disclosed |