Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 15/20 | 0.60 |
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | THPO | P40225 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7328826 | 0.99 | DRD1 (0.59) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL11253637 | 0.86 | DRD1 (0.46) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| SCHEMBL7322313 | 0.81 | CYP2D6 (0.63) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| SCHEMBL11103691 | 0.81 | DRD1 (0.67) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| SCHEMBL11392252 | 0.80 | DRD1 (0.57) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL11268281 | 0.79 | DRD1 (0.56) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| SCHEMBL11162512 | 0.78 | DRD1 (0.71) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| Bromide SCHEMBL11236726 | 0.77 | DRD2 (0.38) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| SCHEMBL7323497 | 0.75 | DRD1 (1.00) | DRD1DRD2CYP2D6TSHRHSD17B10 | |
| SCHEMBL11166758 | 0.75 | DRD1 (0.69) | DRD1DRD2CYP2D6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4192872-A | ANTI -PARKINSONISM ACTIVITY | SMITHKLINE CORPORATION (US) | 1980-03-11 | — | — | US | claimed |