⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359872 | 0.81 | SOAT1 (0.43) | — | |
| SCHEMBL15642200 | 0.81 | ALDH1A1 (0.63) | — | |
| SCHEMBL4542821 | 0.78 | ALDH1A1 (0.52) | — | |
| SCHEMBL7059795 | 0.78 | ALDH1A1 (0.48) | — | |
| SCHEMBL727653 | 0.78 | TDP1 (0.65) | — | |
| SCHEMBL28513647 | 0.78 | ALDH1A1 (0.61) | — | |
| SCHEMBL3137530 | 0.76 | ALDH1A1 (0.50) | — | |
| Ethyl Acetate SCHEMBL10620330 | 0.76 | ALDH1A1 (0.82) | — | |
| Ethyl Acetate SCHEMBL28191643 | 0.76 | ALDH1A1 (0.82) | — | |
| SCHEMBL8826096 | 0.75 | TDP1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550607-B2 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | AUSPEX PHARMACEUTICAL, INC. (US) | 2009-06-23 | — | — | US | claimed |
| US-7264960-B2 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-09-04 | — | — | US | claimed |
| EP-1594835-A4 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS INC (US) | 2007-05-02 | — | — | EP | claimed |
| US-20060173199-A1 | Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses | HONG BORCHERNG | 2006-08-03 | — | — | US | claimed |
| EP-1594835-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | Auspex Pharmaceuticals, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| US-20050026260-A1 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | RESNICK SOL M (US) | 2005-02-03 | — | — | US | claimed |
| EP-1490501-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | Dow Global Technologies Inc. (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
| WO-2003083126-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-09 | — | — | WO | claimed |
| EP-0727494-B1 | Method for the enzymatic acylation of alcohols with alkoxyvinylacetates through transesterification | HOECHST AG (DE) | 1998-09-30 | — | — | EP | claimed |
| US-5756321-A | Process for enzymatic acylation of alcohols with alkoxyvinyl acetates by transesterification | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | claimed |
| JP-10057094-A | — | — | None | — | — | JP | disclosed |
| EP-4627099-A2 | PROCESS FOR MAKING FLAVANONE DERIVATIVES | Firmenich SA (CH) | 2025-10-08 | — | — | EP | disclosed |
| US-12247239-B2 | Chemo-enzymatic process for the preparation of homopropargylic alcohol | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2025-03-11 | — | — | US | disclosed |
| WO-2024115469-A2 | PROCESS FOR MAKING FLAVANONE DERIVATIVES | FIRMENICH SA (CH) | 2024-06-06 | — | — | WO | disclosed |
| US-20040209931-A1 | Process for preparing the enantiomeric forms of cis-configured 1,3-cyclohexanediol derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-21 | — | — | US | disclosed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | disclosed |
| WO-2003083126-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-09 | — | — | WO | disclosed |
| US-5756321-A | Process for enzymatic acylation of alcohols with alkoxyvinyl acetates by transesterification | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| JP-H1057094-A | ENZYMATIC OPTICAL RESOLUTION OF ALCOHOL USING KETENE ACETAL TYPE ACYLATING AGENT | KITA YASUYUKI | 1998-03-03 | — | — | JP | disclosed |