SCHEMBL733023

SCHEMBL733023

C=C(C)C(=O)NCCC.C=C(C)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
EPHX1 P07099 2/20 0.36
PAOX Q6QHF9 1/20 0.35
MCL1 Q07820 1/20 0.35
NPC1 O15118 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TGFBR1 P36897 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
CTSD P07339 1/20 0.32
LMNA P02545 1/20 0.32
KDM4E B2RXH2 2/20 0.32
KMT2A Q03164 2/20 0.32
DPP7 Q9UHL4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL6354454 0.94 TDP1 (0.40) TDP1MMP1MMP2MMP3MMP9
Methylamine SCHEMBL2363145 0.91 MMP1 (0.40) TDP1MMP1MMP2MMP3MMP9
SCHEMBL149370 0.91
Guanidine SCHEMBL28149619 0.90 TDP1 (0.37) TDP1MMP1MMP2MMP3MMP9
Propionamide SCHEMBL6358221 0.90 TDP1 (0.37) TDP1MMP1MMP2MMP3MMP9
Methylamine SCHEMBL6561969 0.89 MMP1 (0.39) TDP1MMP1MMP2MMP3MMP9
Ammonia Solution, Strong SCHEMBL27993992 0.89 MMP1 (0.41) MMP1MMP2MMP3MMP9EPHX1
Hydrochloric Acid SCHEMBL3148805 0.89 MMP1 (0.41) MMP1MMP2MMP3MMP9EPHX1
Dimethylamine SCHEMBL42843 0.87 MMP1 (0.40) MMP1MMP2MMP3MMP9EPHX1
Hydrochloric Acid SCHEMBL28010702 0.87 MMP1 (0.40) MMP1MMP2MMP3MMP9EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3063210-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS SOLVAY SA (BE) 2016-09-07 EP disclosed
US-9388282-B2 Method of thiophenol removal from poly(arylene sulfide) polymer compositions SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2016-07-12 US disclosed
WO-2015065906-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-05-07 WO disclosed
US-20150119550-A1 Method of Thiophenol Removal from Poly(Arylene Sulfide) Polymer Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-04-30 US disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-20120130040-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2012-05-24 US disclosed
EP-2448990-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME Polymeright Inc. (US) 2012-05-09 EP disclosed
US-8138278-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2012-03-20 US disclosed
US-20110152492-A1 Polymer Compositions and Methods of Making and Using Same POLYMERIGHT, INC. (US) 2011-06-23 US disclosed
WO-2011008480-A1 POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING SAME POLYMERIGHT, INC. (US) 2011-01-20 WO disclosed
US-7585932-B2 Polymer compositions and processes for making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-09-08 US disclosed
EP-1940917-A2 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2008-07-09 EP disclosed
US-20070055033-A1 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2007-03-08 US disclosed
WO-2007021960-A2 POLYMER COMPOSITIONS AND PROCESSES FOR MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-02-22 WO disclosed
US-4421782-A WEAR RESISTANT FLOORING ARMSTRONG WORLD INDUSTRIES, INC. (US) 1983-12-20 US disclosed
US-4420499-A N-VINYL LACTAM AND SURFACTANT SOLUTION CURABLE BY ACTINIC RADIATION ARMSTRONG WORLD INDUSTRIES, INC. (US) 1983-12-13 US disclosed