Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PTPRF | P10586 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24124718 | 0.94 | HTT (0.62) | HTTTSHRCYP3A4CYP1A2MEN1 | |
| SCHEMBL22628164 | 0.89 | HTT (0.71) | HTTCYP3A4CYP1A2MEN1CYP2C9 | |
| N-Benzylaniline SCHEMBL7840 | 0.89 | HTT (0.71) | HTTCYP3A4CYP1A2MEN1CYP2C9 | |
| N-Benzylaniline SCHEMBL2176624 | 0.86 | HTT (0.68) | HTTCYP3A4CYP1A2MEN1CYP2C9 | |
| N-Benzylaniline SCHEMBL27620362 | 0.86 | HTT (0.68) | HTTCYP3A4CYP1A2MEN1CYP2C9 | |
| N-Benzylaniline SCHEMBL3602124 | 0.86 | HTT (0.68) | HTTCYP3A4CYP1A2MEN1CYP2C9 | |
| N-Benzylaniline SCHEMBL357137 | 0.86 | HTT (0.68) | HTTCYP3A4CYP1A2MEN1CYP2C9 | |
| SCHEMBL19091942 | 0.84 | FFAR1 (0.63) | HTTTSHRCYP3A4CYP1A2MEN1 | |
| N-Benzylaniline SCHEMBL10963734 | 0.84 | HTT (0.65) | HTTCYP3A4CYP1A2MEN1CYP2C9 | |
| SCHEMBL22620565 | 0.84 | FFAR1 (0.54) | HTTTSHRCYP3A4CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |