Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333909 | 0.97 | DRD2 (0.52) | DRD2DRD3DRD4GRIN2BGRIN1 | |
| SCHEMBL7329375 | 0.96 | DRD2 (0.52) | DRD2DRD3DRD4GRIN2BGRIN1 | |
| SCHEMBL7334552 | 0.94 | DRD2 (0.58) | DRD2DRD3DRD4GRIN2BDRD1 | |
| SCHEMBL7328620 | 0.88 | DRD2 (0.59) | DRD2DRD3DRD4GRIN2BDRD1 | |
| SCHEMBL7326249 | 0.87 | DRD2 (0.49) | DRD2DRD3DRD4GRIN2BDRD1 | |
| SCHEMBL7327607 | 0.85 | GRIN2B (0.54) | DRD2DRD3DRD4GRIN2BGRIN1 | |
| SCHEMBL7328894 | 0.85 | DRD2 (0.58) | DRD2DRD3DRD4GRIN2BDRD1 | |
| SCHEMBL7333090 | 0.84 | DRD2 (0.57) | DRD2DRD3DRD4GRIN2BDRD1 | |
| SCHEMBL7328153 | 0.83 | DRD2 (0.67) | DRD2DRD3DRD4DRD1HTR1A | |
| SCHEMBL7326705 | 0.83 | GRIN2B (0.48) | DRD2DRD3DRD4GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402923-A2 | 2,5-Diaminotetralines, process for their preparation and their use as medicine | BOEHRINGER INGELHEIM KG (DE) | 1990-12-19 | — | — | EP | disclosed |