Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.61 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328928 | 0.93 | PRSS1 (0.55) | PRSS1TMPRSS15MAPTKMT2ACYP1A2 | |
| SCHEMBL28359563 | 0.87 | CASP6 (0.57) | MAPTKMT2ACYP1A2CYP2C9CA12 | |
| Guanidine SCHEMBL1486812 | 0.86 | MAPT (0.68) | MAPTKMT2ACYP1A2CYP2C9CA12 | |
| SCHEMBL11363725 | 0.85 | MAPT (0.54) | PRSS1TMPRSS15MAPTKMT2ACYP1A2 | |
| SCHEMBL7325158 | 0.85 | PRSS1 (0.56) | PRSS1TMPRSS15MAPTKMT2AF10 | |
| SCHEMBL30727558 | 0.82 | MAPT (0.71) | MAPTKMT2ACYP1A2CYP2C9CA12 | |
| SCHEMBL527543 | 0.82 | MAPT (0.71) | MAPTKMT2ACYP1A2CYP2C9CA12 | |
| SCHEMBL7319750 | 0.82 | PRSS1 (0.66) | PRSS1TMPRSS15MAPTKMT2ALMNA | |
| SCHEMBL11474202 | 0.82 | MAPT (0.61) | MAPTKMT2ACYP1A2CYP2C9CA12 | |
| SCHEMBL27727201 | 0.81 | MAPT (0.52) | MAPTKMT2ACYP1A2CYP2C9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |