SCHEMBL7330431

SCHEMBL7330431

CC(C)CNC(=O)C(N)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
DPP4 P27487 2/20 0.45
DPP8 Q6V1X1 2/20 0.45
DPP9 Q86TI2 2/20 0.45
DPP7 Q9UHL4 2/20 0.45
FAP Q12884 1/20 0.45
MMP1 P03956 1/20 0.43
MMP8 P22894 1/20 0.43
SLC7A5 Q01650 1/20 0.42
HPGD P15428 1/20 0.40
ANPEP P15144 2/20 0.39
DNPEP Q9ULA0 1/20 0.39
EPHX1 P07099 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 2/20 0.37
GAA P10253 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3374178 1.00 CYP2D6 (0.50) CYP2D6CYP2C19DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL7328608 0.98 CYP2D6 (0.48) CYP2D6CYP2C19DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL7328602 0.98 CYP2D6 (0.48) CYP2D6CYP2C19DPP4DPP8DPP9
SCHEMBL24648940 0.86 DPP4 (0.47) CYP2D6CYP2C19DPP4DPP8DPP9
SCHEMBL3165650 0.84 DPP4 (0.44) CYP2D6CYP2C19DPP4DPP8DPP9
SCHEMBL8621036 0.84 DPP4 (0.44) CYP2D6CYP2C19DPP4DPP8DPP9
SCHEMBL14577486 0.84 CYP2D6 (0.48) CYP2D6CYP2C19MMP1MMP8HPGD
SCHEMBL19318467 0.83 DPP4 (0.42) CYP2D6CYP2C19DPP4DPP8DPP9
SCHEMBL19319050 0.83 DPP4 (0.42) CYP2D6CYP2C19DPP4DPP8DPP9
SCHEMBL19319054 0.83 DPP4 (0.42) CYP2D6CYP2C19DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1990000399-A1 RETROVIRAL PROTEASE BINDING PEPTIDES SMITHKLINE BECKMAN CORPORATION (US) 1990-01-25 WO disclosed
EP-0352000-A2 Retroviral protease binding peptides SMITHKLINE BEECHAM CORPORATION (US) 1990-01-24 EP disclosed