SCHEMBL733045

SCHEMBL733045

COC(N)CN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3292391 0.73
SCHEMBL7080542 0.71
SCHEMBL65965 0.71
SCHEMBL28386893 0.69
SCHEMBL2104477 0.69
Hydrochloric Acid SCHEMBL7524961 0.69
SCHEMBL4581130 0.69
SCHEMBL8083381 0.69
SCHEMBL15261006 0.69
SCHEMBL24458127 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181077-A Synthetic method of vortioxetine with low impurity content 安徽峆一药业股份有限公司 2022-10-14 CN claimed
CN-119285696-A Preparation method of carbon dioxide response type organic nanotube 华东理工大学 2025-01-10 CN disclosed
US-20230157166-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-05-18 US disclosed
US-20230157166-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-05-18 US disclosed
US-10703746-B2 Mutant IDH1 inhibitors useful for treating cancer THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2020-07-07 US disclosed
US-10421954-B2 Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same NEW YORK UNIVERSITY (US) 2019-09-24 US disclosed
WO-2018102885-A1 MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS AND USES THEREOF BIONOMICS LIMITED (AU) 2018-06-14 WO disclosed
US-20170015991-A1 HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME NEW YORK UNIVERSITY 2017-01-19 US disclosed
US-9458449-B2 Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same NEW YORK UNIVERSITY (US) 2016-10-04 US disclosed
US-20150044189-A1 HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME NEW YORK UNIVERSITY 2015-02-12 US disclosed
US-8138330-B2 Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite SIGMA-ALDRICH CO. LLC (US) 2012-03-20 US disclosed
WO-2008043853-A2 PHOTOCHROMIC FILM OPCO GMBH (DE) 2008-04-17 WO disclosed
US-20080064867-A1 PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES SIGMA ALDRICH COMPANY (US) 2008-03-13 US disclosed
CN-1370154-A Aminothiazole derivatives and their use as CRF receptor ligands SANOFI SYNTHELABO (FR) 2002-09-18 CN disclosed
US-5191015-A Solid phase synthesis on crosslinked polymer, removal of crosslinks to solubilize MEDICAL RESEARCH COUNCIL (GB) 1993-03-02 US disclosed
EP-0394318-A1 POLYMERS AND POLYMER-PEPTIDE CONJUGATES MEDICAL RESEARCH COUNCIL (GB) 1990-10-31 EP disclosed
WO-1989005305-A1 POLYMERS AND POLYMER-PEPTIDE CONJUGATES 3I RESEARCH EXPLOITATION LIMITED (GB) 1989-06-15 WO disclosed
US-4508861-A CONTAINING ANTIOXIDANT SELECTED FROM HINDERED PHENOLS, ARYL PHOSPHONITES, ORGANIC PHOSPHITES, THIOESTERS OR MIXTURES GENERAL ELECTRIC COMPANY (US) 1985-04-02 US disclosed