Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422463 | 0.83 | SMN1; SMN2 (0.50) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL6153970 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27822973 | 0.81 | MAPT (0.44) | MEN1KMT2APOLBSLC6A4HTT | |
| SCHEMBL7584692 | 0.81 | MAPT (0.42) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL11425982 | 0.80 | TSHR (0.51) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL3049742 | 0.80 | TP53 (0.49) | MEN1KMT2APOLBPKMHTT | |
| SCHEMBL6152726 | 0.77 | POLB (0.44) | MEN1KMT2APOLBHTTALDH1A1 | |
| SCHEMBL11415004 | 0.77 | PDE1C (0.51) | KMT2APOLBHTTALDH1A1LMNA | |
| SCHEMBL3788583 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL16954054 | 0.75 | POLB (0.49) | MEN1KMT2APOLBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | claimed |
| EP-1772493-B1 | AZO DYE | FUJIFILM CORP (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-1965255-B1 | Color filter and method for making the color filter | FUJIFILM CORP (JP) | 2015-08-12 | — | — | EP | disclosed |
| US-8968973-B2 | Color filter and production method thereof, and solid-state image sensor using the same | FUJIFILM CORPORATION (JP) | 2015-03-03 | — | — | US | disclosed |
| CN-104114537-A | Substituted benzylamine compounds, their use in medicine, and in particular the treatment of hepatitis c virus (hcv) infection | ASTEX THERAPEUTICS LTD | 2014-10-22 | — | — | CN | disclosed |
| US-20140288040-A1 | SUBSTITUTED BENZYLAMINE COMPOUNDS, THEIR USE IN MEDICINE, AND IN PARTICULAR THE TREATMENT OF HEPATITIS C VIRUS (HCV) INFECTION | ASTEX THERAPEUTICS LIMITED (GB) | 2014-09-25 | — | — | US | disclosed |
| EP-2773613-A1 | SUBSTITUTED BENZYLAMINE COMPOUNDS, THEIR USE IN MEDICINE, AND IN PARTICULAR THE TREATMENT OF HEPATITIS C VIRUS (HCV) INFECTION | Astex Therapeutics Limited (GB) | 2014-09-10 | — | — | EP | disclosed |
| US-8608842-B2 | Infrared absorbing composition, infrared absorbing ink, recorded article, image recording method, and image detecting method | FUJIFILM CORPORATION (JP) | 2013-12-17 | — | — | US | disclosed |
| EP-2629149-A2 | Colored curable composition, color filter and manufacturing method thereof | Fujifilm Corporation (JP) | 2013-08-21 | — | — | EP | disclosed |
| WO-2013064538-A1 | SUBSTITUTED BENZYLAMINE COMPOUNDS, THEIR USE IN MEDICINE, AND IN PARTICULAR THE TREATMENT OF HEPATITIS C VIRUS (HCV) INFECTION | ASTEX THERAPEUTICS LIMITED (GB) | 2013-05-10 | — | — | WO | disclosed |
| US-20070037796-A1 | e.g. 7-Phenyl-isoquinoline-5-sulfonic acid {2-[3 -(4-nitrophenyl)-propylamino]-ethyl}-amide, dihydrochloride salt; antiviral, antineoplastic, anticarcinogenic agents; neoplasms | ELI LILLY AND COMPANY | 2007-02-15 | — | — | US | disclosed |
| EP-1564259-A1 | Azo dye, colored curable composition, color filter and producing method therefor | FUJI PHOTO FILM CO., LTD. (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-20050175908-A1 | Azo dye, colored curable composition, color filter and producing method therefor | FUJI PHOTO FILM CO., LTD. | 2005-08-11 | — | — | US | disclosed |
| US-4463173-A | ANTIBIOTIC, BACTERICIDE | ICI PHARMA (FR) | 1984-07-31 | — | — | US | disclosed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | disclosed |
| EP-0031708-A2 | Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor | ICI PHARMA (FR) | 1981-07-08 | — | — | EP | disclosed |
| US-4156086-A | INTERMEDIATES FOR AZO DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |
| US-4038268-A | DIAZOTIZATION, COUPLING | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4006128-A | CELLULOSE ACETATES, VINYL POLYMERS, POLYOLEFINS, POLYESTERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288040-A1 | SUBSTITUTED BENZYLAMINE COMPOUNDS, THEIR USE IN MEDICINE, AND IN PARTICULAR THE TREATMENT OF HEPATITIS C VIRUS (HCV) INFECTION | NR1H4, CFH, SLC10A1 | MEN1 2004/4885KMT2A 1852/4885POLB 2352/4885 |
| US-20070037796-A1 | e.g. 7-Phenyl-isoquinoline-5-sulfonic acid {2-[3 -(4-nitrophenyl)-propylamino]-ethyl}-amide, dihydrochloride salt; antiviral, antineoplastic, anticarcinogenic agents; neoplasms | POLI, HRAS, CHUK | MEN1 2522/4885KMT2A 1770/4885POLB 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.