Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA7 | P43166 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | PLAU | P00749 | 6/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | PLAT | P00750 | 4/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4424415 | 0.86 | CA1 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL403210 | 0.84 | CA12 (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2807745 | 0.82 | CA12 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20943963 | 0.82 | PRSS1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27437528 | 0.82 | KDM4E (0.46) | PLAUF2F10PLATHPGD | |
| SCHEMBL7332938 | 0.81 | F10 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1647438 | 0.81 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31258831 | 0.81 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL330670 | 0.81 | CA12 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2803617 | 0.81 | CA12 (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4570006-A | ANTITHROMBIN; ENZYME AND HORMONE INHIBITORS | TORII & CO. LTD. (JP) | 1986-02-11 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |