Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330862 | 1.00 | GABRA1 (0.51) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7328808 | 0.90 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7328800 | 0.90 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL8602404 | 0.88 | PAK4 (0.42) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL8602399 | 0.88 | PAK4 (0.42) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7334074 | 0.88 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7334082 | 0.88 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7362181 | 0.84 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7328859 | 0.84 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7329687 | 0.84 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729469-B1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | UPJOHN CO (US) | 1998-09-23 | — | — | EP | claimed |
| US-5594140-A | Imidazo[1,5-A]quinolines for treatment of anxiety and sleep disorders | THE UPJOHN COMPANY (US) | 1997-01-14 | — | — | US | claimed |
| EP-0729469-A1 | IMIDAZO [1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 1996-09-04 | — | — | EP | claimed |
| WO-1995014020-A1 | IMIDAZO[1,5-a]QUINOLINES FOR TREATMENT OF ANXIETY AND SLEEP DISORDERS | THE UPJOHN COMPANY (US) | 1995-05-26 | — | — | WO | claimed |