Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 7/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329793 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL7328817 | 0.80 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL7330895 | 0.73 | ELANE (0.54) | ALDH1A1MAPTKMT2AMEN1ELANE | |
| SCHEMBL7337980 | 0.72 | NPSR1 (0.36) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL7304482 | 0.68 | ELANE (0.52) | ALDH1A1NPSR1KMT2AMEN1TSHR | |
| SCHEMBL7339821 | 0.68 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL8870910 | 0.67 | ELANE (0.40) | ALDH1A1ELANE | |
| SCHEMBL7332181 | 0.65 | KMT2A (0.45) | ALDH1A1MAPTNPSR1KMT2AMEN1 | |
| SCHEMBL8872235 | 0.65 | ELANE (0.49) | ALDH1A1NPSR1ELANESMN1; SMN2 | |
| SCHEMBL7303924 | 0.64 | ELANE (0.44) | ALDH1A1NPSR1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494925-A | TREATING DEGENERATIVE DISORDERS; PROTEOLYTIC ENZYME INHIBITOR | STERLING WINTHROP INC. (US) | 1996-02-27 | — | — | US | disclosed |