Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.42 |
| ▸ | NMUR1 | Q9HB89 | 4/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320110 | 0.86 | CTSD (0.50) | CTSDCTSENMUR2NMUR1 | |
| SCHEMBL7332264 | 0.85 | MAGI3 (0.43) | CTSDKISS1R | |
| SCHEMBL10376833 | 0.83 | NMUR2 (0.51) | F2NMUR2NMUR1KISS1RKDM1A | |
| SCHEMBL7326543 | 0.82 | NMUR2 (0.41) | CTSDCTSEF2NMUR2NMUR1 | |
| SCHEMBL34460905 | 0.77 | NMUR2 (0.58) | NMUR2NMUR1 | |
| SCHEMBL31497329 | 0.77 | CALCRL (0.62) | NMUR2CALCRLKISS1RKDM1A | |
| SCHEMBL7124762 | 0.76 | NMUR2 (0.52) | F2NMUR2NMUR1KISS1RKDM1A | |
| SCHEMBL8441486 | 0.75 | KDM1A (0.54) | F2NMUR2NMUR1KISS1RKDM1A | |
| SCHEMBL10378303 | 0.75 | HRH1 (0.41) | F2NMUR2NMUR1KISS1R | |
| SCHEMBL10377187 | 0.75 | NMUR2 (0.50) | NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |