SCHEMBL733116

SCHEMBL733116

C=C(C)C(=O)OC1CCCCC1OC(=O)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
SERPINE1 P05121 2/20 0.36
GPX4 P36969 1/20 0.35
TSHR P16473 3/20 0.34
EPHX1 P07099 2/20 0.33
THRB P10828 1/20 0.32
ATM Q13315 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
CHRM2 P08172 3/20 0.32
CHRM4 P08173 3/20 0.32
CHRM1 P11229 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8626000 0.98 ALDH1A1 (0.41) ALDH1A1SERPINE1GPX4TSHREPHX1
SCHEMBL10524835 0.95 ALDH1A1 (0.42) ALDH1A1SERPINE1GPX4TSHRTHRB
SCHEMBL2759861 0.92 ALDH1A1 (0.41) ALDH1A1SERPINE1GPX4TSHRKDM4E
SCHEMBL809282 0.91 ALDH1A1 (0.46) ALDH1A1GPX4TSHRTHRBATM
SCHEMBL31495862 0.89 CHRM2 (0.45) ALDH1A1GPX4EPHX1TDP1POLB
SCHEMBL15623955 0.89 ALDH1A1 (0.39) ALDH1A1SERPINE1GPX4ATMKMT2A
SCHEMBL151295 0.88 CYP19A1 (0.42) ALDH1A1GPX4TSHREPHX1NPC1
SCHEMBL5502908 0.88 GSR (0.40) ALDH1A1GPX4TSHRATMTDP1
SCHEMBL23853053 0.87 ALDH1A1 (0.33) ALDH1A1SERPINE1GPX4
SCHEMBL15081601 0.87 ALDH1A1 (0.42) ALDH1A1SERPINE1GPX4EPHX1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4769431-A Polyacryloxyalkylsilanol lens composition, articles and method of manufacture PARAGON OPTICAL INC. (US) 1988-09-06 US claimed
US-4582884-A Lens composition, article and method of manufacture PARAGON OPTICAL, INC. (US) 1986-04-15 US claimed
CN-110997612-A Iron-catalyzed cross-coupling of methanol with secondary or tertiary alcohols to produce formates 伊士曼化工公司 2020-04-10 CN disclosed
US-9469759-B2 Thermoplastic resin composition and molded article using the same SAMSUNG SDI CO., LTD. (KR) 2016-10-18 US disclosed
EP-3063210-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS SOLVAY SA (BE) 2016-09-07 EP disclosed
US-9388282-B2 Method of thiophenol removal from poly(arylene sulfide) polymer compositions SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2016-07-12 US disclosed
US-20160002455-A1 Thermoplastic Resin Composition and Molded Article Using the Same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2016-01-07 US disclosed
WO-2015065906-A2 METHOD OF THIOPHENOL REMOVAL FROM POLY(ARYLENE SULFIDE) POLYMER COMPOSITIONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-05-07 WO disclosed
US-20150119550-A1 Method of Thiophenol Removal from Poly(Arylene Sulfide) Polymer Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-04-30 US disclosed
US-8889802-B2 Polymer compositions and methods of making and using same POLYMERIGHT, INC. (US) 2014-11-18 US disclosed
US-8545981-B2 Artificial hair made of flame-retardant polyester KANEKA CORPORATION (JP) 2013-10-01 US disclosed
CN-1149258-C Transparent rubber modified polystyrene resin composite 奇美实业股份有限公司 2004-05-12 CN disclosed
US-20020115762-A1 Polycarbonate resin composition containing titanium dioxide and sulfone sulfonate salt CHEIL INDUSTRIES, INC. (KR) 2002-08-22 US disclosed
CN-1337419-A Transparent rubber modified polystyrene resin composite QIMEI IND CO LTD (CN) 2002-02-27 CN disclosed
EP-1095983-A1 Polycarbonate resin composition having high impact resistance Cheil Industries Inc. (KR) 2001-05-02 EP disclosed
US-4879348-A IMPACT MODIFICATION OF THERMOPLASTIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1989-11-07 US disclosed
EP-0263633-A2 Crosslinked and grafted overpolymer acrylate rubbers THE DOW CHEMICAL COMPANY (US) 1988-04-13 EP disclosed
EP-0096412-A2 Thermoplastic acrylic resin composition MITSUBISHI RAYON CO., LTD. (JP) 1983-12-21 EP disclosed
US-4217385-A Resinous polymer sheet materials having selective, surface decorative effects and methods of making the same CONGOLEUM CORPORATION (US) 1980-08-12 US disclosed
US-3980627-A POLYACRYLIC ESTER MONOMER; INORGANIC SALT INITIATOR; AN ACCELERATOR; AND A POLYMERIZATION INHIBITOR FELT PRODUCTS MFG. CO. (US) 1976-09-14 US disclosed