Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.58 |
| ▸ | ITGAV | P06756 | 1/20 | 0.58 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | NMBR | P28336 | 2/20 | 0.47 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326462 | 1.00 | ITGB3 (0.58) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7443877 | 0.88 | ITGB3 (0.57) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7331527 | 0.85 | ITGB3 (0.54) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL7323153 | 0.84 | ITGB3 (0.65) | ITGB3ITGA2B | |
| SCHEMBL7255952 | 0.76 | NMBR (0.63) | MEN1KMT2ANMBR | |
| SCHEMBL7350160 | 0.76 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL7350173 | 0.76 | ITGB3 (0.69) | ITGB3ITGA2B | |
| SCHEMBL13717015 | 0.75 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL7251691 | 0.74 | NMBR (0.61) | MEN1KMT2ANMBR | |
| SCHEMBL8906481 | 0.74 | ITGB3 (0.73) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550159-A | Peptide mimics useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5453440-A | Amidine functional group on benzene ring, anticoagulants | G. D. SEARLE & CO. (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1993018058-A1 | PEPTIDES MIMICS USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-09-16 | — | — | WO | disclosed |