Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23665140 | 0.82 | RECQL (0.56) | RECQLCYP1A2KMONPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29687779 | 0.81 | RECQL (0.54) | RECQLCYP1A2KMONPC1RAB9A | |
| SCHEMBL13217 | 0.80 | RECQL (0.61) | RECQLCYP1A2KMONPC1RAB9A | |
| SCHEMBL6006431 | 0.78 | RECQL (0.51) | RECQLCYP1A2KMONPC1RAB9A | |
| SCHEMBL5565705 | 0.77 | CYP1A2 (0.62) | RECQLCYP1A2KMONPC1RAB9A | |
| SCHEMBL29487638 | 0.77 | CYP1A2 (0.62) | RECQLCYP1A2KMONPC1RAB9A | |
| SCHEMBL6008598 | 0.75 | RECQL (0.51) | RECQLCYP1A2KMONPC1RAB9A | |
| SCHEMBL6361653 | 0.74 | ADRA2A (0.49) | RECQLCYP1A2KMONPC1RAB9A | |
| SCHEMBL1326630 | 0.74 | CYP1A2 (0.58) | RECQLCYP1A2KMOPOLBHSD17B10 | |
| SCHEMBL7331551 | 0.74 | RECQL (0.69) | RECQLCYP1A2KMONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543517-A | VIRICIDES | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-08-06 | — | — | US | claimed |