Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 9/20 | 0.62 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | ALPL | P05186 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351258 | 1.00 | RARB (0.67) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7334165 | 0.99 | RARB (0.64) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL2368000 | 0.99 | RARB (0.64) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL2367633 | 0.96 | RARB (0.60) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL12243198 | 0.91 | ALPL (0.57) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL7329944 | 0.89 | ALPL (0.67) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL2349458 | 0.89 | ALPL (0.67) | RARBTP53TSHRPLA2G4BPLA2G4A | |
| SCHEMBL2368455 | 0.88 | ALPL (0.68) | RARBTP53TSHRALPLCYP1A2 | |
| SCHEMBL12243212 | 0.87 | ALPL (0.60) | RARBPLA2G4BALPLCYP1A2CYP2D6 | |
| SCHEMBL12243303 | 0.87 | ALPL (0.68) | RARBTP53PLA2G4BALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-B1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |